Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

The swamp eel, Monopterus albus, can survive in high concentrations of ammonia (>75 mmol l(-1)) and accumulate ammonia to high concentrations in its brain (4.5 µmol g(-1)). Na(+)/K(+)-ATPase (Nka) is an essential transporter in brain cells, and since NH4(+) can substitute for K(+) to activate Nka...

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Bibliographic Details
Main Authors: Xiu L Chen, Nicklaus L J E Wee, Kum C Hiong, Jasmine L Y Ong, You R Chng, Biyun Ching, Wai P Wong, Shit F Chew, Yuen K Ip
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24391932/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24391932/?tool=EBI

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