Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal.

Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal.

Many species of Gram-positive bacteria use sortase transpeptidases to covalently affix proteins to their cell wall or to assemble pili. Sortase-displayed proteins perform critical and diverse functions for cell survival, including cell adhesion, nutrient acquisition, and morphological development, a...

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Bibliographic Details
Main Authors: Michele D Kattke, Albert H Chan, Andrew Duong, Danielle L Sexton, Michael R Sawaya, Duilio Cascio, Marie A Elliot, Robert T Clubb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5148588?pdf=render

Internet

http://europepmc.org/articles/PMC5148588?pdf=render

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