Methylation of the <it>SPARC </it>gene promoter and its clinical implication in pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>The secreted protein acidic and rich in cysteine (<it>SPARC</it>) plays a pivotal role in regulating cell-matrix interactions and tumor angiogenesis, proliferation, and migration. Detection of <it>SPARC </it>g...

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Bibliographic Details
Main Authors: Lv Shunli, Li Minghui, Cao Jia, Du Yiqi, Li Zhaoshen, Huang Haojie, Song Jian, Gao Jun, Lin Han, Gong Yanfang
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/28