Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

<p>Abstract</p> <p>Background</p> <p>Atrial fibrillation (AF) is the most common arrhythmia. The potassium current I<sub>Ks </sub>is essential for cardiac repolarization. Gain-of-function mutations in K<sub>V</sub>7.1, the pore-forming α-subunit...

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Bibliographic Details
Main Authors: Olesen Morten S, Bentzen Bo H, Nielsen Jonas B, Steffensen Annette B, David Jens-Peter, Jabbari Javad, Jensen Henrik K, Haunsø Stig, Svendsen Jesper H, Schmitt Nicole
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Medical Genetics
Subjects:
Lone AF
Genetics
K<sub>V</sub>7.1
KCNE1
I<sub>Ks </sub>current
Online Access:http://www.biomedcentral.com/1471-2350/13/24

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http://www.biomedcentral.com/1471-2350/13/24

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