SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected up to 17 days after symptom onset in clinical...

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Bibliographic Details
Main Authors: Soren Alexandersen, Anthony Chamings, Tarka Raj Bhatta
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19883-7