KRAS and MAPK1 Gene Amplification in Type II Ovarian Carcinomas

KRAS and MAPK1 Gene Amplification in Type II Ovarian Carcinomas

In this study, we examined the clinical significance of KRAS and MAPK1 amplification and assessed whether these amplified genes were potential therapeutic targets in type II ovarian carcinoma. Using fluorescence in situ hybridization, immunohistochemistry, and retrospectively collected clinical data...

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Bibliographic Details
Main Authors: Noriyuki Ishikawa, Naomi Nakayama, Kouji Iida, Emi Sato, Masako Ishikawa, Tomoka Ishibashi, Atsuko Katagiri, Hiroshi Katagiri, Munmun Rahman, Kentaro Nakayama, Mohammed Tanjimur Rahman, Kohji Miyazaki
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:International Journal of Molecular Sciences
Subjects:
type II ovarian carcinoma
KRAS
MAPK1
gene amplification
survival
MEK inhibitor
Online Access:http://www.mdpi.com/1422-0067/14/7/13748

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http://www.mdpi.com/1422-0067/14/7/13748

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