Resolving the fast kinetics of cooperative binding: Ca2+ buffering by calretinin.

Cooperativity is one of the most important properties of molecular interactions in biological systems. It is the ability to influence ligand binding at one site of a macromolecule by previous ligand binding at another site of the same molecule. As a consequence, the affinity of the macromolecule for...

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Bibliographic Details
Main Authors: Guido C Faas, Beat Schwaller, Julio L Vergara, Istvan Mody
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2229850?pdf=render