Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition
Immune responses to infectious agents are initiated when a pathogen or its components bind to pattern recognition receptors (PRRs). PRR binding sets off a cascade of events that activates immune responses. We now show that, in addition to activating immune responses, PRR signaling also initiates an...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-06-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.01293-20 |