Performance Evaluation of Manual and Automated (MagNA Pure) Nucleic Acid Isolation in HPV Detection and Genotyping Using Roche Linear Array HPV Test

Nucleic acids of human papillomavirus (HPV) isolated by manual extraction method (AmpliLute) and automated MagNA pure system were compared and evaluated with cytohistological findings in 253 women. The concordance level between AmpliLute and MagNA was very good 93.3% (𝜅=0.864, 𝑃<.0001). Overall H...

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Bibliographic Details
Main Authors: Aikaterini Chranioti, Evangelia Aga, Niki Margari, Christine Kottaridi, Asimakis Pappas, Ioannis Panayiotides, Petros Karakitsos
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Infectious Diseases in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2011/931281