Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

Apolipoprotein B (ap1111190) and microsomal triglyceride transfer protein (MTP) are necessary for lipoprotein assembly. ApoB consists of five structural domains, βα1-β1-α2-β2-α3. We propose that MTP contains three structural motifs (N-terminal β-barrel, central α-helix, and C-terminal lipid cavity)...

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Bibliographic Details
Main Authors: M.Mahmood Hussain, Jason Shi, Paul Dreizen
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Lipid Research
Subjects:
protein-protein interactions
protein motifs
domains
abetalipoproteinemia
hypobetalipoproteinemia
apolipoprotein B
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327103

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http://www.sciencedirect.com/science/article/pii/S0022227520327103

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