The Host Genetic Diversity in Malaria Infection

Populations exposed to Plasmodium infection develop genetic mechanisms of protection against severe disease. The clinical manifestation of malaria results primarily from the lysis of infected erythrocytes and subsequent immune and inflammatory responses. Herein, we review the genetic alterations ass...

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Bibliographic Details
Main Authors: Vitor R. R. de Mendonça, Marilda Souza Goncalves, Manoel Barral-Netto
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2012/940616