H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S?

BACKGROUND: S-propargyl-cysteine (SPRC), an H(2)S donor, is a structural analogue of S-allycysteine (SAC). It was investigated for its potential anti-cancer effect on SGC-7901 gastric cancer cells and the possible mechanisms that may be involved. METHODS AND FINDINGS: SPRC treatment significantly de...

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Bibliographic Details
Main Authors: Kaium Ma, Yan Liu, Qing Zhu, Chun-hua Liu, Jun-Li Duan, Benny K-H Tan, Yi Zhun Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3124470?pdf=render