METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

Abstract Background N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC. Methods Expression level of METTL14 was extracted...

Full description

Bibliographic Details
Main Authors: Xiao Yang, Sen Zhang, Changyu He, Pei Xue, Luyang Zhang, Zirui He, Lu Zang, Bo Feng, Jing Sun, Minhua Zheng
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Molecular Cancer
Subjects:
m6A
METTL14
Long non-coding RNA
Colorectal cancer
RNA epigenetics
Online Access:http://link.springer.com/article/10.1186/s12943-020-1146-4

Internet

http://link.springer.com/article/10.1186/s12943-020-1146-4

Similar Items