Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults.

Epidemiological evidence for the role of polyunsaturated fatty-acids (PUFA) in Crohn's disease (CD) is unclear, although the key metabolite leucotriene B4 (LTB(4)) is closely linked to the inflammatory process. We hypothesized that inherited variation in key PUFA metabolic enzymes may modify su...

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Bibliographic Details
Main Authors: Irina Costea, David R Mack, David Israel, Kenneth Morgan, Alfreda Krupoves, Ernest Seidman, Colette Deslandres, Philippe Lambrette, Guy Grimard, Emile Levy, Devendra K Amre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3004960?pdf=render