Recent Progress and Advances in HGF/MET-Targeted Therapeutic Agents for Cancer Treatment

The hepatocyte growth factor (HGF): MET axis is a ligand-mediated receptor tyrosine kinase pathway that is involved in multiple cellular functions, including proliferation, survival, motility, and morphogenesis. Aberrancy in the HGF/MET pathway has been reported in multiple tumor types and is associ...

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Bibliographic Details
Main Authors: Yilong Zhang, Rajul K. Jain, Min Zhu
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Biomedicines
Subjects:
HGF
MET
Online Access:http://www.mdpi.com/2227-9059/3/1/149