Recent Progress and Advances in HGF/MET-Targeted Therapeutic Agents for Cancer Treatment
The hepatocyte growth factor (HGF): MET axis is a ligand-mediated receptor tyrosine kinase pathway that is involved in multiple cellular functions, including proliferation, survival, motility, and morphogenesis. Aberrancy in the HGF/MET pathway has been reported in multiple tumor types and is associ...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-03-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | http://www.mdpi.com/2227-9059/3/1/149 |