Analysis of Parent-of-Origin Effects on the X Chromosome in Asian and European Orofacial Cleft Triads Identifies Associations with DMD, FGF13, EGFL6, and Additional Loci at Xp22.2

Background: Although both the mother's and father's alleles are present in the offspring, they may not operate at the same level. These parent-of-origin (PoO) effects have not yet been explored on the X chromosome, which motivated us to develop new methods for detecting such effects. Orofa...

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Bibliographic Details
Main Authors: Øivind Skare, Rolv T. Lie, Øystein A. Haaland, Miriam Gjerdevik, Julia Romanowska, Håkon K. Gjessing, Astanand Jugessur
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00025/full