Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.

BACKGROUND: Colorectal cancers (CRCs) with microsatellite instability (MSI) are associated with a good prognosis and a high density of tumor-infiltrating lymphocytes (TILs). We have undertaken to determine the link between TIL densities and MSI CRC histologic features. PATIENTS AND METHODS: Using ti...

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Bibliographic Details
Main Authors: David Tougeron, Pauline Maby, Nicolas Elie, Emilie Fauquembergue, Florence Le Pessot, Marie Cornic, Jean-Christophe Sabourin, Pierre Michel, Thierry Frébourg, Jean-Baptiste Latouche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3626697?pdf=render