Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation

Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation

<p>Abstract</p> <p>Background</p> <p>Insulin degrading enzyme (IDE) is implicated in the regulation of amyloid β (Aβ) steady-state levels in the brain, and its deficient expression and/or activity may be a risk factor in sporadic Alzheimer's disease (AD). Although...

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Bibliographic Details
Main Authors: Castaño Eduardo M, Ledesma Maria D, Xu Huaxi, Zhang Xue, Surace Ezequiel I, Leal María C, Bulloj Ayelén, Morelli Laura
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/3/1/22

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http://www.molecularneurodegeneration.com/content/3/1/22

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