LC-UV method to assay raloxifene hydrochloride in rat plasma and its application to a pharmacokinetic study

LC-UV method to assay raloxifene hydrochloride in rat plasma and its application to a pharmacokinetic study

A specific, precise, and accurate LC-UV method was developed and validated to assay raloxifene hydrochloride in rat plasma. Raloxifene was analyzed after liquid-liquid extraction and quantified by reversed phase liquid chromatography (C18 column) using acetonitrile and ammonium acetate buffer 0.05 M...

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Bibliographic Details
Main Authors: Márcia Camponogara Fontana, João Víctor Laureano, Betielli Forgearini, Paula dos Santos Chaves, Bibiana Verlindo de Araujo, Ruy Carlos Ruver Beck
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Raloxifene/pharmacokinetic
Liquid chromatography.
Plasma.
Bioavailability.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100538&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100538&lng=en&tlng=en

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