The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

Small cell lung cancer (SCLC) is an aggressive neuroendocrine carcinoma, designated as a recalcitrant cancer by the National Cancer Institute, in urgent need of new rational therapeutic targets. Previous studies have determined that the basic helix-loop-helix transcription factor achaete-scute homol...

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Bibliographic Details
Main Authors: Min He, Shanshan Liu, Sachith Gallolu Kankanamalage, Mark D. Borromeo, Luc Girard, Adi F. Gazdar, John D. Minna, Jane E. Johnson, Melanie H. Cobb
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317303340

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http://www.sciencedirect.com/science/article/pii/S1936523317303340

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