The Maximum Bite Force for Treatment Evaluation in Severely Affected Adult SMA Patients—Protocol for a Longitudinal Study

The Maximum Bite Force for Treatment Evaluation in Severely Affected Adult SMA Patients—Protocol for a Longitudinal Study

Spinal muscular atrophy (SMA) is a severe neuromuscular disorder characterized by the degeneration of motor neurons in the spinal cord, and comprises a broad clinical spectrum. With the advent of new therapies (e.g., Nusinersen) for patients of all ages and disease stages, sensitive clinical measure...

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Bibliographic Details
Main Authors: Teresa Kruse, Helmar C. Lehmann, Bert Braumann, Gereon R. Fink, Gilbert Wunderlich
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Neurology
Subjects:
spinal muscular atrophy
motor neurons
antisense oligonucleotides
bulbar neuromuscular function
masticatory force
piezoelectric transducer
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00139/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00139/full

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