Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease

Parkinson's disease is the second most common neurodegenerative disease. While age is the most significant risk factor, the exact cause of this disease and the most effective approaches to mitigation remain unclear. It has long been proposed that dopamine may play a role in the pathology of Par...

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Bibliographic Details
Main Authors: Yingying Sun, A. Ninh Pham, Dominic J. Hare, T. David Waite
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
pH
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00859/full