DNA Methylation and Gene Expression of Matrix Metalloproteinase 9 Gene in Deficit and Non-deficit Schizophrenia

DNA Methylation and Gene Expression of Matrix Metalloproteinase 9 Gene in Deficit and Non-deficit Schizophrenia

The biological pathology of deficit schizophrenia (DS) remains unclear. Matrix metalloproteinase 9 (MMP9) might be associated with neural plasticity and glutamate regulation, involved in schizophrenia pathogenesis. This study explores gene expression and DNA methylation of MMP9 in peripheral blood m...

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Bibliographic Details
Main Authors: Ju Gao, Hongwei Yi, Xiaowei Tang, Xiaotang Feng, Miao Yu, Weiwei Sha, Xiang Wang, Xiaobin Zhang, Xiangrong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Genetics
Subjects:
deficit schizophrenia
matrix metalloproteinase-9
DNA methylation
gene expression
negative symptoms
pyrosequencing
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00646/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00646/full

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