B cell development in the bone marrow is regulated by homeostatic feedback exerted by mature B cells

B cell development in the bone marrow is regulated by homeostatic feedback exerted by mature B cells

Cellular homeostasis in the B cell compartment is strictly imposed to balance cell production and cell loss. However, it is not clear whether B cell development in the bone marrow (BM) is an autonomous process or subjected to regulation by the peripheral B cell compartment. To specifically address t...

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Bibliographic Details
Main Authors: Gitit eShahaf, Simona eZisman-Rosen, David eBenhamou, Doron eMelamed, Ramit eMehr
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
Computer Simulation
B lymphocytes
BrdU
mathematical modeling.
homeostatic feedback
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00077/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00077/full

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