A constricted opening in Kir channels does not impede potassium conduction

The transition between conducting and non-conducting states of K+ channels has been explained by conformational changes at the intracellular entrance to the conduction pathway. Here authors demonstrate that control over K+ currents in Kir channels is not explained by the canonical pore-gating model,...

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Bibliographic Details
Main Authors: Katrina A. Black, Sitong He, Ruitao Jin, David M. Miller, Jani R. Bolla, Oliver B. Clarke, Paul Johnson, Monique Windley, Christopher J. Burns, Adam P. Hill, Derek Laver, Carol V. Robinson, Brian J. Smith, Jacqueline M. Gulbis
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16842-0