Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes

Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.

Bibliographic Details
Main Authors: Stefano Stassi, Monica Marini, Marco Allione, Sergei Lopatin, Domenico Marson, Erik Laurini, Sabrina Pricl, Candido Fabrizio Pirri, Carlo Ricciardi, Enzo Di Fabrizio
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09612-0