Hydrazine-Containing Heterocycle Cytochalasan Derivatives From Hydrazinolysis of Extracts of a Desert Soil-Derived Fungus Chaetomium madrasense 375

Hydrazine-Containing Heterocycle Cytochalasan Derivatives From Hydrazinolysis of Extracts of a Desert Soil-Derived Fungus Chaetomium madrasense 375

“Diversity-enhanced extracts” is an effective method of producing chemical libraries for the purpose of drug discovery. Three rare new cytochalasan derivative chaetoglobosins B1-B3 (1–3) were obtained from chemically engineered crude broth extracts of Chaetomium madrasense 375 prepared by reacting w...

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Bibliographic Details
Main Authors: Qingfeng Guo, Jinhua Chen, Yuwei Ren, Zhenhua Yin, Juanjuan Zhang, Baocheng Yang, Xuewei Wang, Wenbing Yin, Wancun Zhang, Gang Ding, Lin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Chemistry
Subjects:
diversity-enhanced
cytochalasans
antiproliferative activity
chaetomium madrasense
hydrazinolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.620589/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.620589/full

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