CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling

CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling

Type 2 diabetes mellitus is a severe public health issue worldwide. It displays a harmful effect on different organs as the eyes, kidneys and neural cells due to insulin resistance and high blood glucose concentrations. To date, the available treatments for this disorder remain limited. Several repo...

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Bibliographic Details
Main Authors: Vanessa Castelli, Laura Brandolini, Michele d’Angelo, Cristina Giorgio, Margherita Alfonsetti, Pasquale Cocchiaro, Francesca Lombardi, Annamaria Cimini, Marcello Allegretti
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
diabetes
obesity
inflammation
glucose uptake
insulin resistance
pharmacological approach
Online Access:https://www.mdpi.com/2073-4409/10/9/2324

Internet

https://www.mdpi.com/2073-4409/10/9/2324

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