Evaluation of the Efficacy and Safety of Vonoprazan in Patients with Nonerosive Gastroesophageal Reflux Disease: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study

Evaluation of the Efficacy and Safety of Vonoprazan in Patients with Nonerosive Gastroesophageal Reflux Disease: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study

Background: For many patients, current treatments do not adequately resolve heartburn in nonerosive reflux disease (NERD). Objective: To compare vonoprazan and placebo with respect to the frequency and severity of heartburn in patients with NERD. Methods: This Phase III, double-blind, placebo-contro...

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Main Authors: Yoshikazu Kinoshita, MD, PhD, Yuuichi Sakurai, MPharm, Madoka Shiino, MPharm, Kentaro Kudou, MS, Akira Nishimura, BSc, MBA, Takuya Miyagi, MD, PhD, Katsuhiko Iwakiri, MD, PhD, Eiji Umegaki, MD, PhD, Kiyoshi Ashida, MD, PhD
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Current Therapeutic Research
Subjects:
gastroesophageal reflux
heartburn
NERD
nonerosive gastroesophageal reflux disease
potassium-competitive acid blockers
vonoprazan
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X1630100X

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http://www.sciencedirect.com/science/article/pii/S0011393X1630100X

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