Scc2/Nipbl hops between chromosomal cohesin rings after loading

Scc2/Nipbl hops between chromosomal cohesin rings after loading

The cohesin complex mediates DNA-DNA interactions both between (sister chromatid cohesion) and within chromosomes (DNA looping). It has been suggested that intra-chromosome loops are generated by extrusion of DNAs through the lumen of cohesin’s ring. Scc2 (Nipbl) stimulates cohesin’s ABC-like ATPase...

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Bibliographic Details
Main Authors: James Rhodes, Davide Mazza, Kim Nasmyth, Stephan Uphoff
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Cohesin
Nipbl
Loop Extrusion
Scc2
Hopping
TADs
Online Access:https://elifesciences.org/articles/30000

Internet

https://elifesciences.org/articles/30000

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