Effects of Single Low Dose of Dexamethasone before Noncardiac and Nonneurologic Surgery and General Anesthesia on Postoperative Cognitive Dysfunction-A Phase III Double Blind, Randomized Clinical Trial.

UNLABELLED:Postoperative cognitive dysfunction (POCD) is a multifactorial adverse event most frequently in elderly patients. This study evaluated the effect of dexamethasone on POCD incidence after noncardiac and nonneurologic surgery. METHODS:One hundred and forty patients (ASA I-II; age 60-87 year...

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Main Authors: Livia Stocco Sanches Valentin, Valeria Fontenelle Angelim Pereira, Ricardo S Pietrobon, Andre P Schmidt, Jean P Oses, Luis V Portela, Diogo O Souza, João Ricardo Nickenig Vissoci, Vinicius Fernando da Luz, Leticia Maria de Araujo de Souza Trintoni, Karen C Nielsen, Maria José Carvalho Carmona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4859565?pdf=render