Human Acquired Aplastic Anemia Patients’ Bone-Marrow-Derived Mesenchymal Stem Cells Are Not Influenced by Hematopoietic Compartment and Maintain Stemness and Immune Properties

Background and Objective. Acquired aplastic anemia (aAA) is a bone marrow failure disorder characterized by pancytopenia and bone marrow aplasia. Bone marrow Mesenchymal Stem Cells (BM-MSCs) are an important component of BM microenvironment, associated with hematopoietic and immune homeostasis. Any...

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Bibliographic Details
Main Authors: Vandana Sharma, Sonali Rawat, Suchi Gupta, Sweta Tamta, Rinkey Sharma, Tulika Seth, Sujata Mohanty
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2021/6678067