Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature

Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature

Abstract Background Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin, and can detect different subsets of disease, with potential to identif...

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Bibliographic Details
Main Authors: Emma C. Derrett-Smith, Viktor Martyanov, Cecilia B. Chighizola, Pia Moinzadeh, Corrado Campochiaro, Korsa Khan, Tammara A. Wood, Pier Luigi Meroni, David J. Abraham, Voon H. Ong, Robert Lafyatis, Michael L. Whitfield, Christopher P. Denton
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Arthritis Research & Therapy
Subjects:
Scleroderma
Genetics
Systemic sclerosis
Vasculopathy
Microarray
Online Access:http://link.springer.com/article/10.1186/s13075-017-1360-7

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http://link.springer.com/article/10.1186/s13075-017-1360-7

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