Effect of Doxycycline Microencapsulation on Buccal Films: Stability, Mucoadhesion and In Vitro Drug Release

The aim of this work was to stabilize doxycycline in mucoadhesive buccal films at room temperature (25 °C). Since doxycycline is susceptible to degradation such as oxidation and epimerization, tablets are currently the only formulation that can keep the drug fully stable at room temperature, while l...

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Bibliographic Details
Main Authors: Venu Gopal Reddy Patlolla, Nikolina Popovic, William Peter Holbrook, Thordis Kristmundsdottir, Sveinbjörn Gizurarson
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/7/2/51