Methylation Profiling of Medulloblastoma in a Clinical Setting Permits Sub-classification and Reveals New Outcome Predictions

Methylation Profiling of Medulloblastoma in a Clinical Setting Permits Sub-classification and Reveals New Outcome Predictions

Medulloblastoma (MB) is the most common childhood malignant brain tumor and is a leading cause of cancer-related death in children. DNA methylation profiling has rapidly advanced our understanding of MB pathogenesis at the molecular level, but assessments in Saudi Arabian (SA)-MB cases are sparse. M...

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Bibliographic Details
Main Authors: Musa Alharbi, Nahla Mobark, Yara Bashawri, Leen Abu Safieh, Albandary Alowayn, Rasha Aljelaify, Mariam AlSaeed, Amal Almutairi, Fatimah Alqubaishi, Ebtehal AlSolme, Maqsood Ahmad, Ayman Al-Banyan, Fahad E. Alotabi, Jonathan Serrano, Matija Snuderl, May Al-Rashed, Malak Abedalthagafi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neurology
Subjects:
medulloblastoma
methylation
non-glial
pediatric
neuro-oncology
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00167/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00167/full

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