A Distance-Based Kernel Association Test Based on the Generalized Linear Mixed Model for Correlated Microbiome Studies

Researchers have increasingly employed family-based or longitudinal study designs to survey the roles of the human microbiota on diverse host traits of interest (e. g., health/disease status, medical intervention, behavioral/environmental factor). Such study designs are useful to properly control fo...

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Bibliographic Details
Main Authors: Hyunwook Koh, Yutong Li, Xiang Zhan, Jun Chen, Ni Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00458/full