Structural propensities of human ubiquitination sites: accessibility, centrality and local conformation.

The existence and function of most proteins in the human proteome are regulated by the ubiquitination process. To date, tens of thousands human ubiquitination sites have been identified from high-throughput proteomic studies. However, the mechanism of ubiquitination site selection remains elusive be...

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Bibliographic Details
Main Authors: Yuan Zhou, Sixue Liu, Jiangning Song, Ziding Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3859641?pdf=render