Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test

Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test

Stx1 toxin is one of the AB5 toxins of Shiga toxin-producing Escherichia coli (STEC) responsible for foodborne intoxication during outbreaks. The single-chain variable fragment (scFv) is the most common recombinant antibody format; it consists of both variable chains connected by a peptide linker wi...

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Bibliographic Details
Main Authors: Daniela Luz, Emerson A. Shiga, Gang Chen, Wagner Quintilio, Fernanda B. Andrade, Andrea Q. Maranhão, Bruna A. Caetano, Thaís Mitsunari, Míriam A. Silva, Letícia B. Rocha, Ana M. Moro, Sachdev S. Sidhu, Roxane M. F. Piazza
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Antibodies
Subjects:
antibody
scFv
Stx1
STEC
Online Access:http://www.mdpi.com/2073-4468/7/1/9

Internet

http://www.mdpi.com/2073-4468/7/1/9

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