Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test
Stx1 toxin is one of the AB5 toxins of Shiga toxin-producing Escherichia coli (STEC) responsible for foodborne intoxication during outbreaks. The single-chain variable fragment (scFv) is the most common recombinant antibody format; it consists of both variable chains connected by a peptide linker wi...
Main Authors: | Daniela Luz, Emerson A. Shiga, Gang Chen, Wagner Quintilio, Fernanda B. Andrade, Andrea Q. Maranhão, Bruna A. Caetano, Thaís Mitsunari, Míriam A. Silva, Letícia B. Rocha, Ana M. Moro, Sachdev S. Sidhu, Roxane M. F. Piazza |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
|
Series: | Antibodies |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4468/7/1/9 |
Similar Items
-
Prevalence and distribution of the stx1, stx2 genes in Shiga toxin producing E. coli (STEC) isolates from cattle
by: Y Tahamtan, et al.
Published: (2010-03-01) -
Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin
by: Joshua C. Bunger, et al.
Published: (2015-06-01) -
Distribution of the stx1 and stx2 genes in Escherichia coli isolated from milk cattle according to season, age, and production scale in southwestern region of Goiás, Brazil
by: M.R.A. Ferreira, et al. -
Caracterização fenotípica de células dendríticas transfectadas com scFv obtido a partir de anticorpo monoclonal anti-idiotípico Ab2-β, que mimetiza o antígeno gp43 de Paracoccidioides brasiliensis
by: Grasielle Pereira Jannuzzi
Published: (2013) -
Caracterização fenotípica de células dendríticas transfectadas com scFv obtido a partir de anticorpo monoclonal anti-idiotípico Ab2-β, que mimetiza o antígeno gp43 de Paracoccidioides brasiliensis
by: Jannuzzi, Grasielle Pereira
Published: (2013)