Danger-Sensing/Patten Recognition Receptors and Neuroinflammation in Alzheimer’s Disease

Fibrillar aggregates and soluble oligomers of both Amyloid-β peptides (Aβs) and hyperphosphorylated Tau proteins (p-Tau-es), as well as a chronic neuroinflammation are the main drivers causing progressive neuronal losses and dementia in Alzheimer’s disease (AD). However, the underlying pathogenetic...

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Bibliographic Details
Main Authors: Anna Chiarini, Ubaldo Armato, Peng Hu, Ilaria Dal Prà
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9036