Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.

The control of RNA stability is a key determinant in cellular gene expression. The stability of any transcript is modulated through the activity of cis- or trans-acting regulatory factors as well as cellular quality control systems that ensure the integrity of a transcript. As a result, invading vir...

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Bibliographic Details
Main Authors: Brooke B Sahin, Denish Patel, Nicholas K Conrad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2832700?pdf=render