Phencyclidine Disrupts the Auditory Steady State Response in Rats.

The Auditory Steady-State Response (ASSR) in the electroencephalogram (EEG) is usually reduced in schizophrenia (SZ), particularly to 40 Hz stimulation. The gamma frequency ASSR deficit has been attributed to N-methyl-D-aspartate receptor (NMDAR) hypofunction. We tested whether the NMDAR antagonist,...

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Bibliographic Details
Main Authors: Emma Leishman, Brian F O'Donnell, James B Millward, Jenifer L Vohs, Olga Rass, Giri P Krishnan, Amanda R Bolbecker, Sandra L Morzorati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4530939?pdf=render