Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
The proteases of flaviviruses are promising targets for development of specific antiviral drugs. Here, the authors report a high resolution crystal structure of the NS2B-NS3 protease of Zika virus that provides insight into substrate and inhibitor binding.
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13410 |