FGF21 Attenuated LPS-Induced Depressive-Like Behavior via Inhibiting the Inflammatory Pathway

FGF21 Attenuated LPS-Induced Depressive-Like Behavior via Inhibiting the Inflammatory Pathway

Major depressive disorder is a serious neuropsychiatric disorder with high rates of recurrence and mortality. Many studies have supported that inflammatory processes play a central role in the etiology of depression. Fibroblast growth factor 21 (FGF21), a member of the fibroblast growth factors (FGF...

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Bibliographic Details
Main Authors: Xue Wang, Liyun Zhu, Jian Hu, Ruili Guo, Shasha Ye, Fei Liu, Dongxue Wang, Yeli Zhao, Aiping Hu, Xiaojie Wang, Kaiming Guo, Li Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
major depressive disorder
depressive-like behavior
FGF21
inflammation
NF-κB signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00154/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00154/full

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