Determination of βS haplotypes in patients with sickle-cell anemia in the state of Rio Grande do Norte, Brazil
βS haplotypes were studied in 47 non-related patients with sickle-cell anemia from the state of Rio Grande do Norte, Brazil. Molecular analysis was conducted by PCR/RFLP using restriction endonucleases XmnI, HindIII, HincII and HinfI to analyze six polymorphic sites from the beta cluster. T...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Genética
2011-01-01
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Series: | Genetics and Molecular Biology |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300009 |