Secreted and transmembrane 1A is a novel co-stimulatory ligand.

Most T cell responses to pathogens or self antigens are modulated through the action of regulatory T cells and tissue-specific inhibitory mechanisms. To this end, several receptor-ligand pairs have evolved which either augment or diminish T cell function. Here we describe the tissue ligand SECTM1A (...

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Bibliographic Details
Main Authors: Duncan Howie, Hugo Garcia Rueda, Marion H Brown, Herman Waldmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769348?pdf=render