Accelerated and Improved Vascular Maturity after Transplantation of Testicular Tissue in Hydrogels Supplemented with VEGF- and PDGF-Loaded Nanoparticles

Accelerated and Improved Vascular Maturity after Transplantation of Testicular Tissue in Hydrogels Supplemented with VEGF- and PDGF-Loaded Nanoparticles

Avascular transplantation of frozen–thawed testicular tissue fragments represents a potential future technique for fertility restoration in boys with cancer. A significant loss of spermatogonia was observed in xeno-transplants of human tissue most likely due to the hypoxic period before revasculariz...

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Bibliographic Details
Main Authors: Federico Del Vento, Jonathan Poels, Maxime Vermeulen, Bernard Ucakar, Maria Grazia Giudice, Marc Kanbar, Anne des Rieux, Christine Wyns
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
testicular tissue transplantation
fertility preservation
VEGF
PDGF
vascular maturity
necrosis inhibitor
Online Access:https://www.mdpi.com/1422-0067/22/11/5779

Internet

https://www.mdpi.com/1422-0067/22/11/5779

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