Shift in the function of netrin-1 from axon outgrowth to axon branching in developing cerebral cortical neurons

Shift in the function of netrin-1 from axon outgrowth to axon branching in developing cerebral cortical neurons

Abstract Background Netrin-1, a multifunctional axon guidance cue, elicits axon outgrowth via one of its receptors deleted in colorectal cancer (DCC) in several types of neurons, including cerebral cortical neurons of embryonic mice. However, we and others have observed de novo formation of axon bra...

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Bibliographic Details
Main Authors: Hideko Matsumoto, Masabumi Nagashima
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Neuroscience
Subjects:
Cortical development
Axon guidance
Axon outgrowth
Axon collateral branching
Netrin-1
Atmospheric scanning electron microscopy
Online Access:http://link.springer.com/article/10.1186/s12868-017-0392-x

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http://link.springer.com/article/10.1186/s12868-017-0392-x

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