Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function.

Group B Streptococcus (GBS) is a leading cause of neonatal sepsis where myocardial dysfunction is an important contributor to poor outcome. Here we study the effects of the GBS pore-forming beta-hemolysin/cytolysin (Bh/c) exotoxin on cardiomyocyte viability, contractility, and calcium transients.HL-...

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Bibliographic Details
Main Authors: Mary E Hensler, Shigeki Miyamoto, Victor Nizet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2409074?pdf=render