Serine Supports IL-1β Production in Macrophages Through mTOR Signaling

Serine Supports IL-1β Production in Macrophages Through mTOR Signaling

Intracellular metabolic programs tightly regulate the functions of macrophages, and previous studies have shown that serine mainly shapes the macrophage function via one-carbon metabolism. However, it is unknown whether serine modulates the macrophage function independent of one-carbon metabolism. H...

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Bibliographic Details
Main Authors: Siyuan Chen, Yaoyao Xia, Fang He, Jian Fu, Zhongquan Xin, Baichuan Deng, Liuqin He, Xihong Zhou, Wenkai Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
macrophage
mTOR
IL-1β
inflammation
serine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01866/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01866/full

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